Hubungan Kadar Serum Elektrolit Natrium terhadap Kadar Kalium dan Klorida pada Pasien Diabetes Mellitus dengan Ulkus Diabetikum

Andika Aliviameita, Hamidah Wardatul Millah

Abstract


Diabetes melitus ditandai dengan terjadinya hiperglikemia dan merupakan kelainan metabolik penyebab berbagai komplikasi. Ulkus diabetikum merupakan komplikasi paling umum dari diabetes mellitus yang mempengaruhi penderitanya selama hidupnya. Tujuan penelitian ini adalah untuk mengetahui hubungan kadar elektrolit natrium terhadap kadar kalium dan klorida pada pasien diabetes mellitus dengan ulkus diabetikum. Jumlah sampel penelitian adalah 30 serum pasien diabetes mellitus dengan ulkus diabetikum yang ada di Rumah Luka Wonoayu Sidoarjo. Penelitian ini dilakukan pada bulan Juli 2022 di Rumah Sakit Siti Hajar Sidoarjo. Pada uji statistik Korelasi Pearson diperoleh hasil tidak terdapat hubungan yang signifikan antara kadar natrium dengan kadar kalium  (r = -0,250; p = 0,182). Namun terdapat hubungan yang signifikan antara kadar natrium dengan kadar klorida (r = 0,604; p = 0,000). Kesimpulan pada penelitian ini adalah terdapat hubungan yang kuat antara kadar natrium dengan kadar klorida pada pasien diabetes mellitus dengan ulkus diabetikum.


Diabetes mellitus is characterized by the occurrence of hyperglycemia and is a metabolic disorder that causes various complications. Diabetic ulcers are the most common complication of diabetes mellitus that affects sufferers throughout their lives. The purpose of this study was to determine the relationship between sodium electrolyte levels and potassium and chloride levels in patients with diabetes mellitus with diabetic ulcers. The number of research samples was 30 serum of diabetes mellitus patients with diabetic ulcers at Rumah Luka Wonoayu Sidoarjo. This research was conducted in July 2022 at the Siti Hajar Sidoarjo Hospital. In the Pearson correlation statistical test, the results showed that there was no significant relationship between sodium levels and potassium levels (r = -0.250; p = 0.182). However, there is a significant relationship between sodium levels and chloride levels (r = 0.604; p = 0.000). The conclusion of this study is that there is a strong relationship between sodium levels and chloride levels in patients with diabetes mellitus with diabetic ulcers.


Keywords


Diabetes mellitus; ulkus diabetikum; elektrolit; natrium; kalium, klorida

Full Text:

PDF

References


Aguirre, Florencia, Niam Han Cho, Alex Brown, Gisela Dahlquist, Sheree Dodd, Trisha Dunning, Michael Hirst, et al. 2013. IDF Diabetes Atlas: Sixth Edition. 6th ed. International Diabetes Federation.

Dong, Xin Yu, Jun Jie Jiang, Meng Jun Liu, and Weiwei Li. 2018. “Analysis and Discussion on the Experimental Data of Electrolyte Analyzer.” E3S Web of Conferences 38. https://doi.org/10.1051/e3sconf/20183801039.

Engwa, Godwill Azeh, Friday Nweke Nwalo, Thom Justus Chidera Attama, Micheal Chinweuba Abonyi, Emmanuela N. Akaniro-Ejim, Marian N. Unachukwu, Ambrose N. Njokunwogbu, and Benjamin Ewa Ubi. 2018. “Influence of Type 2 Diabetes on Serum Electrolytes and Renal Function Indices in Patients.” Journal of Clinical and Diagnostic Research 12 (6): BC13–16. https://doi.org/10.7860/JCDR/2018/35940.11673.

Hosen, Bayejid, Ashikur Rahman Buiyan, Shamimul Hasan, Mahmudul Hassan, and Mesbah Uddin. 2014. “Estimation of Serum Electrolytes in Non Insulin Dependent (Type 2) Diabetic.” Sciemtific Research Journal (Scirj) II (XII): 29–32. https://doi.org/www.scirj.org.

Infodatin. 2020. Tetap Produktif, Cegah dan Atasi Diabetes Mellitus. Jakarta: Pusat Data dan Informasi Kementrian Kesehatan RI.

Khan, Rashid Naseem, Farhana Saba, Syedhh Fatima Kausar, and Muhammad Hassan Siddiqui. 2019. “Pattern of Electrolyte Imbalance in Type 2 Diabetes Patients: Experience from a Tertiary Care Hospital.” Pakistan Journal of Medical Sciences 35 (3): 797–801. https://doi.org/10.12669/pjms.35.3.844.

Lathifah, Nur Lailatul. 2017. “Hubungan Durasi Penyakit dan Kadar Gula Darah dengan Keluhan Subyektif Penderita Diabetes Melitus.” Jurnal Berkala Epidemiologi 5 (2): 218. https://doi.org/10.20473/jbe.v5i2.2017.231-239.

Mubarok, Wahit Iqbal, and Nurul Chayatin. 2005. Buku Ajar Kebutuhan Dasar Manusia Teori dan Aplikasi dalam Praktik. Jakarta: EGC.

Parmar, Kumari, Samir Singh, and Ganesh Singh. 2016. “Role of Hyperglycemia in the Pathogenesis of Na+/K+ Disturbance.” International Journal of Research in Medical Sciences 4 (4): 1167–71. https://doi.org/10.18203/2320-6012.ijrms20160803.

Ramadan, Ragda Hafaz, and Abdulmwla Muhammed Abdullah. 2020. “Assessment of Serum Electrolyte Levels and HbA1C Levels among Type 2 Diabetic Sudanese Patients with Macrovascular Complications in Khartoum State.” OALib 07 (03): 1–9. https://doi.org/10.4236/oalib.1106110.

Schaper, Nicolaas C., Jaap J. van Netten, Jan Apelqvist, Sicco A. Bus, Robert J. Hinchliffe, and Benjamin A. Lipsky. 2020. “Practical Guidelines on the Prevention and Management of Diabetic Foot Disease (IWGDF 2019 Update).” Diabetes/Metabolism Research and Reviews 36 (S1): 1–10. https://doi.org/10.1002/dmrr.3266.

Talabani, Namama. 2014. “Serum Electrolytes and Lipid Profiles in Non-Insulin Dependent Diabetes Mellitus Patients.” Asian Journal of Medical Sciences 6 (3): 38–41. https://doi.org/10.3126/ajms.v6i3.11088.

Wang, Shenqi, Xuhong Hou, Yu Liu, Huijuan Lu, Li Wei, Yuqian Bao, and Weiping Jia. 2013. “Serum Electrolyte Levels in Relation to Macrovascular Complications in Chinese Patients with Diabetes Mellitus.” Cardiovascular Diabetology 12 (1): 1–10. https://doi.org/10.1186/1475-2840-12-146.




DOI: http://dx.doi.org/10.52365/jond.v4i1.881

Article Metrics

Abstract view : 688 times
PDF - 1417 times

Refbacks

  • There are currently no refbacks.


Indexed in: