Formulasi dan Evaluasi Stabilitas Fisik Krim Minyak Biji Kelor (Moringa oleifera L.)
Abstract
Minyak biji kelor merupakan tanaman yang memiliki efek antioksidan karena memiliki kandungan flavanoid yang tinggi, sehingga perlu dilakukan pengembangan minyak biji kelor dalam bentuk sediaan krim. Penelitian ini bertujuan untuk memformulasi serta mengevaluasi sediaan krim. Penelitian ini merupakan penelitian eksperimental laboratorium. Sediaan krim dibuat dengan dengan tiga formula konsentrasi minyak biji kelor yang berbeda yaitu FI (3%); FII (4%); FIII (5%). Evaluasi stabilitas sediaan krim meliputi pengamatan organoleptik (bau, warna, tekstur), uji homogenitas, uji pH, uji viskositas, dan uji daya sebar. Hasil pemeriksaan mutu sediaan organoleptik menunjukkan bahwa semakin tinggi konsentrasi dalam sediaan krim maka semakin kental pula sediaan tersebut, uji homogenitas sediaan menunjukkan susunan yang homogen, uji pH yang dihasilkan 5,8-6,1, uji viskositas sediaan yang dihasilkan 5900 Cp, 5300 Cp, dan 5240 Cp, dan uji daya sebar yang dihasilkan 7 cm, 6,5 cm, 5,5 cm. Maka dapat disimpulkan bahwa FI, FII dan FIII krim minyak biji kelor dapat diformulasikan sebagai sediaan krim.
Moringa seed oil is a plant that has an antioxidant effect because it has a high flavonoid content, so it is necessary to develop Moringa seed oil in the form of cream preparations. This study aims to formulate and evaluate cream preparations. This research is an experimental laboratory research. Cream preparations were made with three different concentration formulas of Moringa seed oil, namely FI (3%); FII (4%); FIII (5%). Evaluation of the stability of the cream preparation included organoleptic observations (smell, color, texture), homogeneity test, pH test, viscosity test, and spreadability test. The results of the quality inspection of organoleptic preparations showed that the higher the concentration in the cream preparation, the thicker the preparation, the homogeneity test of the preparation showed a homogeneous arrangement, the pH test produced was 5.8 -6.1, the viscosity test of the preparation produced 5900 Cp, 5300 Cp , and 5240 Cp, and the resulting dispersion test was 7 cm, 6.5 cm, 5.5 cm. So it can be concluded that FI, FII and FIII Moringa seed oil cream can be formulated as a cream preparation.
Keywords
Full Text:
PDFReferences
Anwar, F, S Latif, M Ashraf, and AH Gilani. 2015. “Moringa Oleifera: A
Food Plant with Multiple Medicinal Uses.” Phytother 21: 17–25
https://doi.org/10.1002/ptr.2023
Dina, A., Pramono, S., Sugihartini, N., 2017. “Optimasi Komposisi
Emulgator dalam Formulasi Krim Fraksi Etil Asetat Ekstrak Kulit
Batang Nangka (Artocarpus heterophyllus Lamk.).” Jurnal Ilmu
Kefarmasian Indonesia, 15(2), 134-139
Herdiani, E. 2012. “Potensi Tanaman Obat Indonesia.” Potensi Tanaman
Obat Indonesia.
Lubis, E.S, and J Reveny. 2012. “Pelembab Kulit Alami dari Sari Buah Jeruk
Bali.” Journal of Pharmaceutics and Pharmacology 1(2): 8–13.
Lumentut, Natalia, Hosea Jaya, and Erladys Melindah. 2018. “Formulasi
dan Uji Stabilitas Fisik Sediaan Krim Ekstrak Etanol Kulit Buah
Pisang Goroho (Musa acuminafe L .) Konsentrasi 12 . 5 % Sebagai
Tabir Surya.” Jurnal MIPA 9 (2): 42–46.
https://doi.org/10.35799/jmuo.9.2.2020.28248
Formulasi dan Evaluasi Krim Minyak Biji Kelor
Mustarichie, R., dan Gozali D. 2019. “Formulation and Evaluation of Alpha
Arbutin Skin Lightening Cream Using Polyacrylate Base by Cold
Process.” Int J App Pharm 11(1), 100-105
https://doi.org/10.22159/ijap.2019v11i1.29393
Pratasik, Meyla C M, Paulina V Y Yamlean, and Weny I Wiyono. 2019.
“Formulasi dan Uji Stabilitas Fisik Sediaan Krim Ekstrak Etanol
Daun Sesewanua (Clerodendron squamatum Vahl.).” Pharmacon 8 (2):
–67. https://doi.org/10.35799/pha.8.2019.29289
Singh, B, B Singh, R Singh, D Prakash, R Dhakarey, and G Upaddhya. 2009.
“Oxidative DNA Damaged Protective Activity, Antioxidant and
Antiquorum Sensing Potensial of Moringa Oleifera.” Food Chem
Toxicol 47(6) https://doi.org/10.1016/j.fct.2009.01.034
Sudaryanto, T Herwanto, and Sely H Putri. 2016. “Aktivitas Antioksidan
pada Minyak Biji Kelor (Moringa oleifera L.) dengan Metode
Sokletasi Menggunakan Pelarut N-Heksan, Metanol dan Etanol.”
Jurnal Teknotan 10 (2): 16–21.
DOI: http://dx.doi.org/10.52365/jecp.v2i2.433
Article Metrics


Refbacks
- There are currently no refbacks.
Copyright (c) 2022 Awalludin Awalludin, Robert Tungadi, Endah Nurrohwinta Djuwarno

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Indexed in:
![]() Journal of Experimental and Clinical Pharmacy (JECP) by Department of Pharmacy, Poltekkes Kemenkes Gorontalo is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. | Support By: |